Loading up his car before a football game in September, Dave White waved goodbye to his partner, Vicky, and two young sons as he did every week — with little idea that his life was about to change dramatically.
A short time later, 30 minutes into the game, the 31-year-old had a heart attack on the pitch.
He’d had no pain or other symptoms beforehand and always considered himself to be healthy and active, walking daily and refereeing football matches once or twice a week.
Yet Dave, from Newport in Shropshire, is not alone.
Experts report a worrying rise in the number of under-40s in the UK having heart attacks.
A heart attack is caused by a sudden loss of blood flow to part of the heart, usually due to a coronary artery becoming blocked. (By contrast, a cardiac arrest, which Dave also experienced, is when the heart suddenly stops pumping due to a dangerous abnormal heart rhythm.)
‘Between 10 to 20 per cent of my heart attack patients are now under the age of 40,’ says Dr Martin Lowe, a consultant cardiologist at St Bartholomew’s Hospital and The Portland Hospital, both in London.
‘In the US, data shows around one in five heart attack patients is under 40 and we’re catching up in the UK.
‘When I was a junior doctor it was extremely rare to see young people — most patients were smokers in their 50s and 60s.’
Dr Joe Mills, a consultant cardiologist at Liverpool Heart and Chest Hospital, adds: ‘We have really noticed the trend for younger people from mid-20s upwards having heart attacks in the past five years in particular.
‘Now as a cardiologist, you wouldn’t even raise your eyebrows when seeing someone in their late 30s — it’s becoming fairly typical, which is frightening.’
So what’s causing the rise in heart attacks in younger people?
A number of factors are to blame, including poor diet and obesity, a sedentary lifestyle, an increase in the number of young people developing type 2 diabetes (which is associated with thicker and stickier blood which raises the risk of blood clots and, in turn, heart attacks), smoking and alcohol, says Dr Lowe.
Obesity often leads to high blood pressure, which can put extra strain on the arteries and heart, and sleep apnoea (disordered patterns of breathing at night that cause you to temporarily stop breathing) can both also lead to blood clots forming.
Another main cause is stress, as Dr Lowe explains: ‘Generally we all live with stress, but it can trigger a heart attack or change in heart rhythm in some people and not others. I’ve seen a huge increase in heart rhythm problems due to stress.’
Professor Thomas Lüscher, a consultant cardiologist at Royal Brompton and Harefield Hospitals in London, says stress activates the sympathetic nervous system, associated with ‘fight or flight’ responses, and this increases our heart rate and can cause the major coronary arteries to contract.
This, in turn, can cause plaque (a substance made of fat and cholesterol which builds up inside the arteries) to rupture, triggering clots to form inside the artery. As the clot grows, it can block blood flow and lead to a heart attack. Dave believes his attack was caused by stress related to his job looking after young people at a children’s care home, and high cholesterol levels that he didn’t know he had.
‘The month before the heart attack, the pressures of my job were getting to me more than they usually do, to the point where I broke down after a shift and was on the verge of resigning,’ he says.
‘The teenagers we look after can have complex needs, so the work can be unpredictable. It was a stressful time.’
As for the day of his heart attack, he says that it had been ‘just a normal day, I’d walked the dog and then I went to referee some football matches — I was feeling fine. The last thing I remember was being on the pitch . . . and then I woke up in hospital five days later’.
Other people at the match later told Dave that he fell over and appeared to have a seizure (this can occur when the brain doesn’t get enough oxygen).
Bystanders gave him CPR and called an ambulance. The paramedics gave him an ECG (an electrocardiogram, a test that records the electrical activity of the heart), which indicated he had a blockage in a coronary artery.
In hospital he was put in an induced coma to protect his brain and allow it to heal after it had been deprived of oxygen. He then had a stent (a short mesh tube) inserted into his left anterior descending artery — the largest artery in the heart — which a scan had revealed was blocked.
‘I was so confused as to why this happened at my age,’ says Dave.
‘I’ve always been active — I walk the dog every day and referee at football weekly without getting breathless.
‘I don’t smoke and hardly drink. I am a bit overweight — maybe by around 2st — but it still didn’t make sense.’
Further tests revealed that despite having no symptoms or history of heart problems in his family, Dave has high cholesterol levels (roughly 8 mmol/L — they should be below five), which raises the risk of heart attacks.
‘My follow-up appointment is this month, and I have so many unanswered questions — such as why do I have high cholesterol,’ he says.
Dave is currently unable to return to his job because the medication he’s been taking since the heart attack (statins, beta blockers, aspirin and blood pressure tablets) have caused side-effects such as breathlessness and abdominal discomfort.
‘Now I’m trying to take better care of myself by eating more healthily and going for longer walks with the dog.
‘Vicky [33, a veterinary nurse] and my sons Harvey, six, and Archie, four, mean everything to me and I want to make sure I’m around for a long time.’ Young people who have heart attacks often have worse outcomes, says Dr Lowe — this is simply because they do not consider they could be having a heart attack and so don’t get the treatment — such as a stent placed in the blocked artery to open it up — quickly enough to minimise long-term heart damage.
A delay in diagnosis raises the risk of a future, bigger and fatal heart attack (subsequent heart attacks are usually more severe while one in three heart attacks is fatal), or heart failure (when the heart cannot pump blood around the body properly), adds Dr Mills.
‘If you’re 35 and living with heart failure, it’s devastating and your life expectancy is dramatically reduced, so it’s a pretty disastrous outcome at that sort of age.’
If someone has chest pain that could be a sign of a heart attack, they should be seen within 30 minutes to give them the greatest chance of a full recovery and restoring normal circulation, advises Dr Lowe.
Heart muscle cells deprived of oxygen can survive if blood flow is restored within 30 minutes; beyond that point, the cells die and are replaced with scar tissue.
‘Younger people almost always fail to recognise symptoms,’ says Dr Mills. ‘Unfortunately, many think they have indigestion when it’s actually a heart attack — they can feel very similar.’
So how can you tell the difference between indigestion or a heart attack?
Dr Lowe says anyone who has never had indigestion before should not assume it is causing their pain, especially if they have any risk factors for heart attack.
‘If symptoms [usually discomfort anywhere above the diaphragm, but most commonly the chest, arms, back, neck or jaw] come on suddenly and last for more than 30 minutes, seem “unusual” or there’s no obvious reason to suspect indigestion — for example you haven’t eaten spicy food or consumed more alcohol than normal — then do not put these symptoms down to indigestion and consider the possibility of a more serious diagnosis such as a heart attack,’ he says.
It’s also important for people with heart-related risk factors, or those with a strong family of heart disease, to get their blood pressure and cholesterol checked — around one in 250 people has a genetic condition which causes very high levels of cholesterol unrelated to diet, known as familial hypercholesterolaemia (FH).
(Dave is currently waiting for an appointment to assess whether or not he has FH.)
‘A lot of people unknowingly have high blood pressure or cholesterol as they don’t have symptoms — and we don’t systematically look for it under the age of 40,’ says Dr Mills.
People of certain ethnicities, particularly those from South Asian countries, are more likely to have heart attacks at a younger age, says Professor Lüscher.
‘They are genetically more likely to be obese, get type 2 diabetes and high blood pressure when they are exposed to a Western lifestyle,’ he explains.
But it’s not just the general public that need to be aware of the risk of heart attack in younger people, many health professionals also don’t recognise the signs, adds Dr Mills.
This leads to people with chest pain being sent home from A&E, only for them to have a major heart attack within a day or two, he adds.
‘A lot of effort has previously been put into making sure healthcare professionals don’t dismiss women with suspected heart attacks, because traditionally heart attacks were thought to affect men — but now we’re getting to the same stage with not dismissing the under-40s.’
• For more information on heart attacks, visit bhf.org.uk
And younger women face risk linked to hormones
Another factor for young women in particular is the risk of spontaneous coronary artery dissection (SCAD), where a bruise or tear develops in a coronary artery which cuts off blood flow and results in a heart attack.
This is impossible to predict or prevent.
It is thought that four people a day in the UK have a heart attack due to SCAD, but they don’t have the usual risk factors associated with heart disease and the condition is not fully understood.
As 90 per cent of those affected are women, particularly during pregnancy, after childbirth or around the menopause, fluctuating levels of female sex hormones are thought to play a role in the condition.
Victoria Warnes, 42, from Maidenhead, Berkshire, thought she had pulled a muscle when she experienced chest pain while out jogging six weeks after giving birth to her second child, Wills, in 2017.
‘It was really painful but it felt similar to when I had pulled a chest muscle in my 20s playing tennis,’ says Victoria, who also has a daughter, Olivia, nine.
But the chest pain was actually a sign of a SCAD, which had blocked her main coronary artery by 97 per cent.
Four days later, when the pain worsened and climbing the stairs made her breathless, she went to A&E — where she had an X-ray and ECG. ‘I was a fit 35-year-old, so they were scratching their heads and couldn’t find anything wrong, so I went home and wasn’t given any advice.’
The next morning, becoming more concerned about the increasing discomfort as it wasn’t normal for her, Victoria managed to get a private appointment with a cardiologist — a CT scan showed the severe blockage in her artery and she was rushed to hospital to have a stent fitted to allow blood to pass through her artery. ‘It was very traumatic,’ she says. ‘I was in complete disbelief and all I could think about were the children.
‘Mentally, I was totally broken afterwards — I was so scared it would happen again.’ Victoria believes stress played a part in her SCAD.
‘I was stressed because my husband Rich [44, a business architect] was away for work and I was looking after a newborn and toddler alone, hardly sleeping, and still recovering from a Caesarean section,’ she recalls.
Victoria had a stressful job at an advertising agency until maternity leave, but since the heart attack she has made big changes.
‘When I was having the stent put in, I promised myself I would reduce the stresses I can control — working crazy hours and commuting into London was one of them,’ explains Victoria, who now has annual appointments to monitor her heart.
She left her job and set up Our Baby Club, antenatal classes which focus on parental wellbeing.
‘It was a gift in the end because if it hadn’t happened, I’d still be burning myself into the ground,’ she says.
I run marathons, never smoke or drink – so why me?
Dr Salman Uddin, 38, a GP, lives in Ilford, with his wife Rumana, 37, also a GP, and their two young children.
He says: ‘I had never had any signs of heart problems — in fact, I considered myself fit and healthy. I regularly ran — I’ve completed three London marathons — had never smoked and didn’t drink alcohol.
‘Then, one weekend in July 2020, I went for a 10K run. I hadn’t been running for a few weeks due to the Covid lockdown rules and so I paced myself.
‘It went smoothly, though I was slightly slower than usual. I figured this was because I hadn’t run in a while.
‘When I got home, I went upstairs to shower, and as I got undressed noticed I was sweating profusely. Rumana came in and saw I looked so wet, she thought I’d already showered! Then I developed a pain in my chest, which quickly spread to my neck.
‘I wondered whether the run had triggered indigestion, so I asked Rumana for a Gaviscon tablet, but she ignored me and called 999.
‘By this time I was sitting on the floor, pain racking my body. Our baby daughter was on the bed gurgling away; she smiled at me and for a moment I was distracted but then the pain hit me in a sudden wave, spreading all down my arm, across my chest and neck.
‘When the paramedics arrived, they seemed jovial and didn’t mention “heart attack”, presumably because I was young and fit. I was able to walk to the ambulance with them, where they hooked me up to an ECG to check my heart activity — and then their faces dropped. Suddenly I was being blue-lit to St Barts Hospital in London.
‘By now the pain was greater, so they gave me morphine as well as aspirin to thin the blood.
‘In hospital I was whisked through for an angiogram — a sort of X-ray on the heart and arteries around it — and it confirmed I had a blockage in an artery. I’d experienced a heart attack.
‘I was shocked, as I’d never had any symptoms, nor did I have any of the obvious risk factors: I was not a smoker, a drinker, nor diabetic, I ran regularly and there was no family history of heart disease. They said it was “one of those things” — there was no obvious cause. The same day, I was taken to the operating theatre, where a cardiologist inserted a stent to open the blocked artery. I was kept in hospital for three days. I was given medication to prevent future attacks, including aspirin, clopidogrel, lansoprazole and candesartan.
‘Afterwards life seemed surreal. I was in shock that this had happened to me — a person who is not a traditional heart attack patient.
‘I spend my life advising patients on losing weight and staying healthy, and now I’d had a heart attack; clearly sometimes they happen despite your best efforts to stay healthy.
‘Now I’m back to running and eating healthily — but I’m telling my story to warn others not to ignore signs of a heart attack, even if you are young, sporty and seemingly healthy.’
- Interview by Julie Cook