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Pfizer, BioNTech dose U.S first participants of trial coronavirus vaccine

Pfizer Inc. and BioNTech SE announced on Wednesday, May 6, 2020, that the first participants have been dosed in the U.S in the Phase 1/2 clinical trial for the BNT162 vaccine program to prevent COVID-19. The trial is part of a global development program, and the dosing of the first cohort in Germany was completed last week. The Phase 1/2 study is designed to determine the safety, immunogenicity and optimal dose level of four mRNA vaccine candidates evaluated in a single, continuous study. The dose level escalation portion (Stage 1) of the Phase 1/2 trial in the U.S will enrol up to 360 healthy subjects into two age cohorts (18-55 and 65-85 years of age). The first subjects immunized in Stage 1 of the study will be healthy adults 18-55 years of age. Older adults will only be immunized with ...

California Governor Allows Some Retail Reopening With Limits

Some Los Angeles County retailers can reopen with curbside pickup only — including stores that sell music, toys, books, clothing and sporting goods. California Gov. Gavin Newsom on Thursday issued the broadest loosening of his stay-at-home order so far, allowing some retailers to reopen but not have customers in stores. The guidelines were made “with an eye on turning the page and moving into a new phase in terms of our economic recovery,” Newsom said. The announcement was the result of improvement in battling the coronavirus. It moves California into the second phase of a methodical four-step process to full reopening. It covers only a sliver of retail businesses as well as manufacturers’ warehouses considered low risk for the virus. Stores that will be allowed to open with curbside...

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