Moderna gave its mRNA-based seasonal flu vaccine to the first set of volunteers in a clinical trial, the pharmaceutical company announced today. The start of the trial marks the next stage of the company’s work on this type of vaccine technology after the overwhelming success of its COVID-19 vaccine, which was built using the same strategy. Before the COVID-19 pandemic, mRNA vaccines were still largely experimental, even as they were heralded as the future of vaccine development. People who get an mRNA vaccine are injected with tiny snippets of genetic material from the target virus. Their cells use that genetic information to build bits of the virus, which the body’s immune system learns to fight against. The high efficacy of the mRNA COVID-19 vaccines made by Moderna and Pfizer / BioNTec...
The coronavirus variant discovered in South Africa may evade the protection provided by Pfizer/BioNTech’s COVID-19 vaccine to some extent, a real-world data study in Israel found, though its prevalence in the country is very low and the research has not been peer reviewed. The study, released on Saturday, compared almost 400 people who had tested positive for COVID-19, 14 days or more after they received one or two doses of the vaccine, against the same number of unvaccinated patients with the disease. It matched age and gender, among other characteristics. The South African variant, B.1.351, was found to make up about 1% of all the COVID-19 cases across all the people studied, according to the study by Tel Aviv University and Israel’s largest healthcare provider, Clalit. But among patient...
Pfizer and BioNTech said Saturday they will limit the delays of their vaccine deliveries to just one week, after fears in Europe that shipments of the jabs could be slowed for up to a month. The US drugmaker and its German partner “have developed a plan that will allow the scale-up of manufacturing capacities in Europe and deliver significantly more doses in the second quarter,” they said in a joint statement. “As a result, our facility in Puurs, Belgium will experience a temporary reduction in the number of doses delivered in the upcoming week.” Pfizer and BioNTech pledged that deliveries would be back to the original schedule to the European Union from the week of January 25, with increased delivery from the week of February 15. “To accomplish this, certain modifications of production pr...
Taiwan says request to drop word ‘country’ preceded BioNTech vaccine deal collapse
Germany’s BioNTech asked Taiwan to remove the word “country” from an announcement they planned to make on a COVID-19 vaccine sale to the island, its health minister said on Thursday, giving details of the deal whose axing was blamed on China by Taipei. Taiwan and China are engaged in an escalating war of words after Beijing offered the shots to the Chinese-claimed island via Shanghai Fosun Pharmaceutical Group Co Ltd, which has a contract to sell them in Greater China. Taiwan Health Minister Chen Shih-chung told a daily news briefing the government had signed and sent back a “final contract” agreed with BioNTech after months of negotiations, and the two sides were on the verge of issuing a press release on Jan. 8. But four hours later “BioNTech suddenly sent a letter, saying they strongly ...